Clinical trials are integral to ECC unique standing as a research-oriented public cancer hospital and the foundation upon which clinical medicine is practiced.

 

Clinical trials are research studies that test new medical treatments. They are used to gather more information about how effective a treatment is for humans and form an important part of ECC role as a research-based cancer hospital.

There are more than 10 clinical trials active in cancer at Erode Cancer Centre at any one time. Trials commonly involve new cancer medicines but also examine new approaches chemotherapy therapy, supportive care, pain control and better ways of detecting the spread of tumours.

ECC clinical trials teams use cutting-edge approaches, including sophisticated cancer imaging technologies, to evaluate the body’s responses to new treatments. This is done safely and in close collaboration with our research laboratories and clinical areas.

PARTICIPATING IN CLINICAL RESEARCH

If you or someone you know has been diagnosed with cancer, you may want to know about clinical trials or other clinical research studies that may be available at Erode cancer centre Research department

INTRODUCTION

At ECC , there are many different types of research studies being undertaken. These include;

  • Clinical trials research, which may include areas of disease prevention, screening, diagnostics and treatment,
  • Cancer experiences type research, which includes;
    • Behavioral research, which looks at how cancer impacts people emotionally and socially, or may examine individual characteristics, lifestyle or other factors that may affect the risk of developing or surviving cancer, and
    • Health service research, which examines how people get access to healthcare professionals and services, how much care costs and what happens to patients as a result of these factors.

For a free practical guide on ‘Understanding Clinical Trials and Clinical Research

 

HOW CAN I GET INVOLVED IN A CLINICAL RESEARCH STUDY?

If you or your cancer doctor find a suitable clinical research study or trial you want to join, you will be asked to supply details to confirm you are eligible for that study. If it looks like you are eligible for a clinical research study, an appointment will be made with your cancer doctor, a research nurse or a researcher working on the study.

Taking part in a study

All clinical research projects have a detailed plan which describes the purpose of the study, how it will be conducted and who can join the study. This is called the ‘study protocol’.

To join a study, there may be certain characteristics or eligibility criteria that must be met. For example, these may be related to age, cancer type, symptoms or side effects experienced, previous medical history etc. Sometimes people are unable to join a study because certain characteristics limit their ability to take part in the trial or may increase the risk of them having a bad reaction to the treatment or intervention, for example if they are pregnant or have high blood pressure etc.

For a clinical trial of a drug or new treatment, you may need a ‘referral’ from your treating cancer doctor.

Informed consent

Before you join a research study, your doctor, nurse or another researcher will ask your permission. The process of giving your permission is called ‘informed consent’. Providing ‘informed consent’ means that you understand the purpose, and the risks and possible outcomes of the study.

Informed consent means that;

Step 1. You have received written information about the study called ‘Participant Information’. This information includes;

  • The purpose of the study
  • Who can or cannot participate in the study
  • Who is running the study, for example the name of the researcher and their research institution
  • Who have approved the study; all clinical research must be approved by a Human Ethics Research Committee
  • Who is funding the research
  • What you need to do in the study, including any tests or other procedures
  • How long the study will last
  • Information about possible side effects or any risks of joining the study
  • Who you can contact if you need further information, or have a problem or complaint
  • How your privacy, and medical and study records and data will be protected in the study
  • Your rights to withdraw from the study

Step 2. Following an explanation of the study you will be given time to read the ‘Participant Information’ and ask any questions you may have about the study. If you agree to take part in the study, you will be asked to sign the study consent form. Signing a consent form is not like signing a contract because you may at any time withdraw from the study at any time – see below.

What can I expect?

At the start
  • You may need to complete some tests to check that the research study is suitable for you. This may include medical tests (for example a blood test) or you may need to complete a questionnaire.
  • You should read the ‘Participant Information’ provided to you. You may want to discuss the information with your family, friends or doctor.
  • You may ask your cancer doctor, the research nurse or the researcher any questions you may have about the study.

Here are some questions you may wish to ask

.

  • You will need to provide ‘informed consent’ to join the study.
During the study
  • Please follow the instructions and directions you have been given for the study. This ensures that the information and results that are collected from you are as accurate and reliable as possible. This may include attending your appointments, taking prescribed medicines and completing questionnaires and other paperwork.
  • You may need to complete more tests and paperwork than you would normally expect. This is because we are monitoring your health and wellbeing while you are participating in the study.
  • You may also participate in an interview which asks you about your experiences, and how you are feeling emotionally and physically.
After the study
  • You may need to complete more tests and paperwork after the study has been completed. This is because the researchers of your study are interested in long-term information about your health and wellbeing.
  • After the study you will return to receiving the type of treatment that is currently the best option for you or you may need to have normal check-ups with your GP (usual doctor). What happens next depends on the stage of your cancer and what your cancer specialist thinks is the best care for you.

If you would like to continue with the experimental treatment, you must ask your cancer specialist whether this is possible. Whether you are able to continue on an experimental treatment after the study is over depends on many things. For example, the stage or phase of the study, the study results and whether the treatment worked for you. In the case of drug or other therapeutic trials, it may also depend on whether the sponsor (for example, the pharmaceutical company) is prepared to continue providing the treatment.

Can I withdraw from a clinical research study?

Yes. You can withdraw from a clinical research study or trial at any time. You can also decide to withdraw from a clinical research study or trial for any reason.

You will not be penalized if you decide to withdraw from a clinical research study or clinical trial. If you withdraw from a clinical research study or clinical trial, you will continue to receive the type of treatment that is currently the best option for you.

Are there other ways to participate in research?

Yes, you may be able to participate in a clinical research study as a ‘consumer representative’.

Consumer representatives can be patients, former patients, and family members and friends of patients.

Consumer representatives support research studies by providing a consumers’ perspective. This is an important role that helps us achieve better health and research outcomes.

FURTHER INFORMATION

Indian Cancer Trials Online: free information service displaying the latest clinical trials in cancer care across India

Indian Clinical Trials: A federal government site with general information for the public, researchers and industry

Cancer Cooperative Trials Groups: These groups conduct world-class multi-disciplinary research for cancer control to inform clinical practice and improve the survival and quality of life of cancer patients.

Cancer Council India and State and Territory Councils: These groups undertake a broad range of activities including research (and funding research), developing and providing to cancer patients and the broader community resources, developing and supporting cancer prevention and early detection programs, providing patient support and more.

  • Cancer Council India
  • Cancer Council Indian Capital Territory
  • Cancer Council NSW
  • Cancer Council Qld
  • Cancer Council SA
  • Cancer Council Tasmania
  • Cancer Council Northern Territory
  • Cancer Council Victoria (CCV)
  • Cancer Council WA

 

Consumer Learning: This website was developed by the federal government to enhance the contribution of people affected by cancer to clinical trials research

Medicines India: Representing the Indian pharmaceutical industry, this website includes a list of questions and answers about clinical research

National Cancer Institute (NCI): The NCI coordinates the National Cancer Program in the U.S.A. Their website contains useful information including discussion topics, statistics, a comprehensive cancer glossary and resources for caregivers.

CLINICAL RESEARCH FACILITATION

Erode Cancer Centre a driving force in linking patient care with cancer research.

Its unique fabric, which has research embedded and enmeshed within a public hospital dedicated to cancer care, provides the ideal platform to be a world-leading comprehensive cancer centre and excel in translating research findings to the bedside and beyond.

As the only cancer research site embedded in a specialist public cancer hospital in India, ECC’s perpetual cancer research cycle is unique in India; clinicians take their observations from the clinic and share them with their laboratory colleagues, and in turn, researchers plan their research directions with patients in mind.

Early research in the laboratory

Erode Cancer Centre researchers ask a broad range of questions to better understand, and aim to control, the molecular processes behind the onset and progression of cancer, including finding ways to better predict and detect cancer, to give everyone the best chance of effective treatment and lasting immunity.

New therapies through clinical trials

Laboratory researchers forge partnerships with radiation oncologists, imaging specialists, and medical and surgical oncologists, to advance new therapies and new combinations of treatments that have been effective in pre-clinical models to the human setting.

Research in the clinic, at the bedside and beyond

Erode Cancer Centre researchers adapt, complement, strengthen and moderate existing treatments to provide maximum effect on cancer while causing minimal harm to healthy tissue, while also improving the holistic patient experience, addressing broader psycho-social needs, and refining pain management and palliative care.

Our cancer research cycle is unique in India, and illustrates the diverse range of paths that ideas and discoveries to the benefit of cancer patients everywhere.

ECC’s research is enabled by expert staff and cutting-edge infrastructure.

 

 

 

STARTING A NEW PROJECT

The aim of the Research department is to ensure that the following essential building blocks are facilitated when starting a new project, which include but are not limited to:

  • facilitate study procurement
  • protocol review
  • assist with sponsor contract and budget negotiation
  • facilitate submission of new research proposals to ethics committees and governance
  • assist in closeout of research projects
  • provide compliance oversight in the area of sponsor regulations
  • Offer training and education in research administration and compliance.

Erode Cancer Centre promotes and fosters the optimal integrity of its research, which is conducted in accordance with the Indian Code for the Responsible Conduct of Research .

Queries or concerns regarding research conduct at Erode Cancer Centre can be sent to ecc.crc@gmail.com

 

HEAD OF THE RESEARCH DEPARTMENT

Dr.K.VELAVAN

Principal Investigator

Email: kvels@redffimail.com